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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1986-8-8
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pubmed:abstractText |
The natural history of isocyanate-induced asthma is not well documented. We evaluated a patient who developed persistent shortness of breath, wheezing, and cough after a massive exposure to toluene diisocyanate (TDI). Despite no further occupational exposures to isocyanates, he continued to have symptoms of asthma and variable airway obstruction 12 yr later. A methacholine inhalation challenge test was markedly positive, and a bronchial challenge test to TDI produced a dual asthmatic response. This report demonstrates that sensitivity to TDI can persist for many years in the absence of further occupational exposure and suggests that some patients with TDI-induced asthma do not recover from their disease after being removed from isocyanate exposure.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
134
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
175-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3014935-Asthma,
pubmed-meshheading:3014935-Bronchial Provocation Tests,
pubmed-meshheading:3014935-Cyanates,
pubmed-meshheading:3014935-Humans,
pubmed-meshheading:3014935-Male,
pubmed-meshheading:3014935-Methacholine Chloride,
pubmed-meshheading:3014935-Methacholine Compounds,
pubmed-meshheading:3014935-Middle Aged,
pubmed-meshheading:3014935-Occupational Diseases,
pubmed-meshheading:3014935-Time Factors,
pubmed-meshheading:3014935-Toluene 2,4-Diisocyanate
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pubmed:year |
1986
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pubmed:articleTitle |
Persistent airways disease caused by toluene diisocyanate.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
|