Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6074
|
pubmed:dateCreated |
1986-8-15
|
pubmed:abstractText |
Splicing of the Tetrahymena ribosomal intron was first studied by Cech et al., who subsequently demonstrated that the intron RNA catalyses its own excision from a primary transcript to yield mature ribosomal RNA. This intron shares several short conserved sequences and a common secondary structure with several other introns, some of which have also been shown to self-splice. Here I show that the conserved core of the Tetrahymena intron can act in trans to catalyse the sequence-specific cleavage and addition of guanosine to a separate RNA substrate.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0028-0836
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
322
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
83-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3014350-Animals,
pubmed-meshheading:3014350-Base Sequence,
pubmed-meshheading:3014350-Chromosome Deletion,
pubmed-meshheading:3014350-DNA Restriction Enzymes,
pubmed-meshheading:3014350-Guanosine Triphosphate,
pubmed-meshheading:3014350-Magnesium,
pubmed-meshheading:3014350-Nucleic Acid Conformation,
pubmed-meshheading:3014350-RNA, Ribosomal,
pubmed-meshheading:3014350-RNA Splicing,
pubmed-meshheading:3014350-Tetrahymena
|
pubmed:articleTitle |
Enzymatic activity of the conserved core of a group I self-splicing intron.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|