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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1986-5-30
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pubmed:abstractText |
The protease gene structure and the env gene variability have been precisely compared between the AIDS virus and members of the HTLV/BLV family. The conserved amino acid sequence (LVDT) which is repeated in the proteases of the HTLV/BLV family is not repeated in AIDS virus. Comparative analysis of the env gene sequences reveals the striking fact that the env gene of AIDS virus is 8-12-times more variable than those of the HTLV/BLV family. Within the AIDS virus env gene, the surface glycoprotein region is more liable to vary than is the transmembrane region; unexpectedly, however, this liability is not a characteristic feature of the AIDS virus because it is more prominent in other retroviruses including members of the HTLV/BLV family.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
21
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pubmed:volume |
199
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-50
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:3009215-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:3009215-Deltaretrovirus,
pubmed-meshheading:3009215-Genes,
pubmed-meshheading:3009215-Genes, Viral,
pubmed-meshheading:3009215-Genetic Variation,
pubmed-meshheading:3009215-Humans,
pubmed-meshheading:3009215-Peptide Hydrolases,
pubmed-meshheading:3009215-Phylogeny,
pubmed-meshheading:3009215-Retroviridae,
pubmed-meshheading:3009215-Viral Envelope Proteins
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pubmed:year |
1986
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pubmed:articleTitle |
Protease gene structure and env gene variability of the AIDS virus.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|