Linked Life Data

3008955

Source:http://linkedlifedata.com/resource/pubmed/id/3008955

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-5-27
pubmed:abstractText
Light microscopic autoradiography of bound radiolabeled ligands was used to describe the distribution of six receptor types in the dorsal and ventral mouse cochlear nuclei: Glycine receptor ([3H]strychnine); GABA receptor ([3H]muscimol); benzodiazepine receptor ([3H]flunitrazepam); adenosine receptor ([3H]cyclohexyladenosine); muscarinic ACh receptor ([3H]quinuclidinyl benzilate); histamine receptor ([3H]mepyramine). The most intense [3H]strychnine labeling was observed in the deep region of the dorsal cochlear nucleus (DCN), with slightly lower levels in the molecular and pyramidal layers. Highest density of [3H]muscimol binding sites was observed in the granule cell layer of the posterior ventral nucleus (PVCN) and in the pyramidal layer of the DCN. Diffuse [3H]flunitrazepam labeling was distributed over all laminar regions of the DCN; the highest grain density was observed over the granule cell layer of the PVCN. Intense [3H]cyclohexyladenosine labeling was seen over the molecular layer, possibly extending into the pyramidal layer, of the DCN. The granule cell layer of the PVCN was also densely labeled. High concentrations of [3H]quinuclidinyl benzilate sites were seen in the molecular layer, possibly extending into the pyramidal layer, of the DCN. A thin band of high grain density was also visible over the granule cell layer of the PVCN. Moderate, diffuse [3H]mepyramine labeling was visible throughout the DCN, with slightly higher grain density over the molecular, and possibly the pyramidal layers, than over the deep region of the DCN.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0361-9230
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-203
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Autoradiographic localization of receptors in the cochlear nucleus of the mouse.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.