Linked Life Data

3007348

Source:http://linkedlifedata.com/resource/pubmed/id/3007348

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-5-19
pubmed:abstractText
Pst I RFLP, revealed with DQ alpha and DQ beta probes, was compared with Taq I RFLP using a panel of DR-homozygous cell lines and HLA-typed family members. Taq I patterns, characteristic for each DR-associated DQ alpha and beta allelic forms, were recognized in the homozygous state and then proven to segregate in the heterozygous members of informative families. The presence of both specific alpha and beta chains was found to be necessary to form the type of DQ molecule specifically recognized by two alloreactive T-cell clones. Particular alpha and beta associations also seem to be responsible for some Dw splits of the DRw6-positive cells. Taq I RFLP analysis may be more complex than the Pst I analysis, but is certainly more informative and complete, considering the type of information we were seeking by performing these types of experiments.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0093-7711
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-96
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
DQ alpha and beta RFLP reveals the composition of the DQ molecule recognized by T-cell clones.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.