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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1986-4-29
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pubmed:abstractText |
[3H]-yohimbine binding sites were quantified in platelets from Parkinsonians with no clinical signs of dysautonomia. Never-treated Parkinsonians had a lower specific binding than control subjects. This alteration was associated with decreased epinephrine-induced platelet aggregation. Treatment with dopaminergic agents induced a significant increment of [3H]-yohimbine binding sites. These results show that Parkinson's disease is associated with a reduced number of peripheral alpha 2 adrenoceptors and that dopaminergic agents induce partial recovery.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
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pubmed:issn |
0014-2972
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
403-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3007161-Aged,
pubmed-meshheading:3007161-Blood Platelets,
pubmed-meshheading:3007161-Bromocriptine,
pubmed-meshheading:3007161-Cell Membrane,
pubmed-meshheading:3007161-Female,
pubmed-meshheading:3007161-Humans,
pubmed-meshheading:3007161-Levodopa,
pubmed-meshheading:3007161-Male,
pubmed-meshheading:3007161-Middle Aged,
pubmed-meshheading:3007161-Parkinson Disease,
pubmed-meshheading:3007161-Platelet Aggregation,
pubmed-meshheading:3007161-Receptors, Adrenergic, alpha,
pubmed-meshheading:3007161-Yohimbine
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pubmed:year |
1985
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pubmed:articleTitle |
Platelet alpha 2 adrenoceptors in Parkinson's disease: decreased number in untreated patients and recovery after treatment.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|