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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1986-3-28
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pubmed:abstractText |
The autopsy findings in a case of hepatocellular carcinoma with hepatitis B virus (HBV)-DNA integration in a Japanese boy, 4 years and 10 month of age, are reported. The boy was an HBV carrier born in a typical familial cluster of HBV infection in Japan. He had been asymptomatic until the sudden manifestation of the liver tumor. Histopathologic examination revealed a well-differentiated, adult-type hepatocellular carcinoma without hepatic cirrhosis. HBV-DNA sequences were detected in the tumor cell DNA by the Southern blot hybridization method. This is the youngest patient with hepatocellular carcinoma with HBV-DNA integration reported to date, suggesting that HBV may manifest its oncogenic properties after a shorter incubation period than generally believed.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0046-8177
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
202-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3005156-Antigens, Viral,
pubmed-meshheading:3005156-Carcinoma, Hepatocellular,
pubmed-meshheading:3005156-Child, Preschool,
pubmed-meshheading:3005156-DNA, Neoplasm,
pubmed-meshheading:3005156-DNA, Viral,
pubmed-meshheading:3005156-Genetic Code,
pubmed-meshheading:3005156-Hepatitis B,
pubmed-meshheading:3005156-Hepatitis B virus,
pubmed-meshheading:3005156-Humans,
pubmed-meshheading:3005156-Liver Neoplasms,
pubmed-meshheading:3005156-Male,
pubmed-meshheading:3005156-Nucleic Acid Hybridization
|
pubmed:year |
1986
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pubmed:articleTitle |
Primary hepatocellular carcinoma with hepatitis B virus-DNA integration in a 4-year-old boy.
|
pubmed:publicationType |
Journal Article,
Case Reports
|