Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1986-3-14
|
pubmed:abstractText |
Using affinity cross-linking techniques, we report the presence of type I IGF and type II IGF receptors in Madin-Darby canine kidney cells, a line of cells lacking insulin receptors. The IGF receptors were further characterized by competition binding studies and found to be similar to IGF receptors in other tissue types. In Madin-Darby canine kidney cells, the type I IGF receptor binds IGF-I greater than IGF-II greater than insulin and the type II IGF receptor binds IGF-II and IGF-I with approximately the same affinity, but does not bind insulin.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0006-291X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
14
|
pubmed:volume |
134
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
120-7
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:3004425-Animals,
pubmed-meshheading:3004425-Binding, Competitive,
pubmed-meshheading:3004425-Cell Line,
pubmed-meshheading:3004425-Dogs,
pubmed-meshheading:3004425-Insulin,
pubmed-meshheading:3004425-Insulin-Like Growth Factor I,
pubmed-meshheading:3004425-Kidney,
pubmed-meshheading:3004425-Molecular Weight,
pubmed-meshheading:3004425-Receptors, Cell Surface,
pubmed-meshheading:3004425-Receptors, Somatomedin
|
pubmed:year |
1986
|
pubmed:articleTitle |
Madin-Darby canine kidney cells display type I and type II insulin-like growth factor (IGF) receptors.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|