Linked Life Data

3003580

Source:http://linkedlifedata.com/resource/pubmed/id/3003580

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6053
pubmed:dateCreated
1986-3-21
pubmed:abstractText
The genetic relationships of human populations have been studied by comparing gene frequency data for protein and blood-group loci of different populations. DNA analysis now promises to be more informative since not only do the DNA coding sequences have more variation than their corresponding proteins but, in addition, noncoding DNA sequences display more extensive polymorphism. We have now studied the frequency of a group of closely linked nuclear DNA polymorphisms (haplotypes) in the beta-globin gene cluster of normal (beta A) chromosomes of individuals from eight diverse populations. We have found that all non-African populations share a limited number of common haplotypes whereas Africans have predominantly a different haplotype not found in other populations. Genetic distance analysis based on these nuclear DNA polymorphisms indicates a major division of human populations into an African and a Eurasian group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:volume
319
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
491-3
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:articleTitle
Evolutionary relationships of human populations from an analysis of nuclear DNA polymorphisms.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't