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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1986-2-19
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pubmed:abstractText |
Permissive mouse 3T6 cells were exposed to polyoma virus--either wild-type or early mutant--at high multiplicities of infection. From colonies arising from surviving cells, so-called lines and clones were derived under conditions precluding superinfection. These lines and clones were examined for the presence of viral genetic information, using a variety of techniques. Two salient findings were made: most lines or clones analyzed had retained viral genetic material; generally, this material was nondefective, as evidenced by the production of virus and/or viral DNA molecules of genomic size. These findings indicate that mouse cells can survive for many generations while carrying a complete, infectious, and potentially cytocidal polyoma virus genome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0168-1702
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-18
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3002065-Animals,
pubmed-meshheading:3002065-Cell Survival,
pubmed-meshheading:3002065-Cell Transformation, Viral,
pubmed-meshheading:3002065-Cells, Cultured,
pubmed-meshheading:3002065-Clone Cells,
pubmed-meshheading:3002065-DNA, Viral,
pubmed-meshheading:3002065-DNA Restriction Enzymes,
pubmed-meshheading:3002065-Genes, Viral,
pubmed-meshheading:3002065-Mice,
pubmed-meshheading:3002065-Mutation,
pubmed-meshheading:3002065-Nucleic Acid Hybridization,
pubmed-meshheading:3002065-Polyomavirus,
pubmed-meshheading:3002065-Protein Biosynthesis,
pubmed-meshheading:3002065-Species Specificity
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pubmed:year |
1985
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pubmed:articleTitle |
Mouse cells surviving polyoma virus infection generally retain the whole viral genome.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|