Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1986-2-19
|
pubmed:abstractText |
We have isolated, sequenced, and determined the chromosomal localization of the gene encoding human lymphotoxin (LT). The single copy gene was isolated from a human genomic library using a 32P-labeled 116 bp synthetic DNA fragment whose sequence was based on the NH2-terminal amino acid sequence of LT. The gene spans 3 kb of DNA and is interrupted by three intervening sequences. The LT gene is located on human chromosome 6, as determined by Southern blot analysis of human-murine hybrid DNA. Putative transcriptional control regions and areas of homology with the promoters of interferon and other genes are identified.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0730-2312
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
171-81
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:3001109-Amino Acid Sequence,
pubmed-meshheading:3001109-Base Sequence,
pubmed-meshheading:3001109-Chromosome Mapping,
pubmed-meshheading:3001109-Chromosomes, Human, 6-12 and X,
pubmed-meshheading:3001109-Cloning, Molecular,
pubmed-meshheading:3001109-DNA Restriction Enzymes,
pubmed-meshheading:3001109-Genes,
pubmed-meshheading:3001109-Humans,
pubmed-meshheading:3001109-Lymphotoxin-alpha,
pubmed-meshheading:3001109-Poly A,
pubmed-meshheading:3001109-Promoter Regions, Genetic,
pubmed-meshheading:3001109-RNA Caps,
pubmed-meshheading:3001109-Sequence Homology, Nucleic Acid
|
pubmed:year |
1985
|
pubmed:articleTitle |
Structure and chromosomal localization of the human lymphotoxin gene.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|