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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1986-1-29
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pubmed:abstractText |
The iron storage ferritin light-chain gene exhibits multiple restriction enzyme fragments which have been mapped by analyzing sorted human chromosomes. A dual laser chromosome sorter was used to construct spot-blot filter panels representing 22 chromosome fractions. Hybridization of radiolabeled human ferritin-L gene probe to spot-blot panels revealed the ferritin-L gene on more than one chromosome. Miniaturized restriction enzyme analysis was used to map each of the ferritin-L restriction fragments uniquely to one of three chromosomes. This combination of sorted chromosome analyses provides a rapid method to map homologous DNA sequences located on more than one chromosome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0340-6717
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
325-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3000916-Base Sequence,
pubmed-meshheading:3000916-Chromosome Mapping,
pubmed-meshheading:3000916-Chromosomes, Human, 19-20,
pubmed-meshheading:3000916-DNA,
pubmed-meshheading:3000916-DNA Restriction Enzymes,
pubmed-meshheading:3000916-Ferritins,
pubmed-meshheading:3000916-Flow Cytometry,
pubmed-meshheading:3000916-Genetic Markers,
pubmed-meshheading:3000916-Humans
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pubmed:year |
1985
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pubmed:articleTitle |
Human ferritin light chain gene sequences mapped to several sorted chromosomes.
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pubmed:publicationType |
Journal Article
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