Linked Life Data

299990

Source:http://linkedlifedata.com/resource/pubmed/id/299990

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-3-15
pubmed:abstractText
Pieces of isolated stratum corneum from frog skins were studied. Preliminary data showed that approximately 56% of the total sodium of split skins was associated with the stratum corneum. In more detailed studies, the sodium space estimated with 22Na and the volume of tissue water were identical, averaging 0.95 mul/cm2. Thus, the stratum corneum contained approximately 0.11 mueq Na+/cm2. Similar determinations of the sucrose, mannitol, and inulin spaces of the stratum corneum gave mean values of 0.84, 2.21, and 1.84 mul/cm2, respectively. Surprisingly, the mannitol and inulin spaces were observed to be at least twice as large as the space occupied by the tissue water, and this can be interpreted to mean that mannitol and inulin bind in appreciable amounts and thus are unsuitable markers of the sodium space. Whereas the kinetics of sodium uptake and washout could be described simply, similar studies for sucrose, mannitol, and inulin were more complex and consistent with appreciable binding of the substances to the stratum corneum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
232
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
C37-44
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Stratum corneum of frog skin: inferences for studies of Na entry and transport pool.
pubmed:publicationType
Journal Article, In Vitro