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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1986-1-17
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pubmed:abstractText |
We used bacteria-derived bovine alpha-interferon I1 (Bo IFN-alpha I1) to study its antiviral effect in a bovine turbinate cell line on bovine diarrhea virus, infectious bovine rhinotracheitis virus, parainfluenza 3 virus, and pseudorabies virus. We based our study upon replicate tests for each strain by using a block titration system with various concentrations of Bo IFN-alpha I1 against various concentrations of virus. The data were compiled in two-axis tables (replicate X concentration) and were statistically analyzed by the Spearman-Kärber method. An increase in the concentration of Bo IFN-alpha I1 enhanced its protective effect against every test virus strain. Bo IFN-alpha I1 had a marked in vitro effect on the bovine diarrhea viral strains. It demonstrated less protection against the pseudorabies and parainfluenza 3 viruses. Its effectiveness against the two infectious bovine rhinotracheitis viral strains was lesser and of a low order.
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pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0095-1137
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
912-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2999188-Animals,
pubmed-meshheading:2999188-Cattle,
pubmed-meshheading:2999188-Cell Line,
pubmed-meshheading:2999188-Diarrhea Viruses, Bovine Viral,
pubmed-meshheading:2999188-Herpesvirus 1, Bovine,
pubmed-meshheading:2999188-Herpesvirus 1, Suid,
pubmed-meshheading:2999188-Interferon Type I,
pubmed-meshheading:2999188-Parainfluenza Virus 3, Human,
pubmed-meshheading:2999188-Viruses
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pubmed:year |
1985
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pubmed:articleTitle |
In vitro protective effect of bacteria-derived bovine alpha interferon I1 against selected bovine viruses.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|