Linked Life Data

2997326

Source:http://linkedlifedata.com/resource/pubmed/id/2997326

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-11-25
pubmed:abstractText
As judged by restriction analysis, mitochondrial DNA shows strictly maternal inheritance during 6-8 generations of backcrossing in both directions between Mus domesticus and Mus spretus. The average number of paternal mitochondrial genomes contributed to the next generation is estimated to be no more than one per thousand maternal mitochondrial genomes contributed. Despite the estimated accumulation of over 2000 mutational differences between M. spretus and M. domesticus mtDNAs since their divergence from a common ancestor, each of these mitochondrial DNAs, whether on a M. spretus or a M. domesticus nuclear background, allows mice to develop with seemingly normal viability and fertility.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0022-1503
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Maternal inheritance of mitochondrial DNA during backcrossing of two species of mice.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't