Linked Life Data

2997320

Source:http://linkedlifedata.com/resource/pubmed/id/2997320

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-12-19
pubmed:abstractText
This review summarizes recent progress in the knowledge of catecholamines in cirrhosis. Compensated patients have normal plasma concentration of noradrenaline. Highly elevated plasma noradrenaline concentration in decompensated patients indicates that the sympathetic nervous system is enhanced in this condition. This may especially apply to the sympathetic tone in the kidney, as evaluated by regional measurements of noradrenaline overflow. Hepatic elimination of catecholamines is only slightly reduced. Activation of the sympathetic nervous system seems to play an important role in the avid sodium-water retention and decreased kidney perfusion observed in decompensated cirrhosis. Volume- en baro-receptors are likely to elicit this overactivity. The decreased systemic arterial blood pressure may be a primary event which is in part counteracted by enhanced sympathetic nervous activity and activated renin-angiotensin system. The role of a non-volume-dependent hepatic baro-receptor, false neurotransmitters, postsynaptic receptors, and autonomous neuropathy are yet unknown issues of further research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0168-8278
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-65
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Sympathetic nervous activity in cirrhosis. A survey of plasma catecholamine studies.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't