Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1985-11-25
|
pubmed:abstractText |
Unitary, presynaptic spike potentials were observed in single cell recordings from the dorsal lateral geniculate nucleus of the cat. In 11 cells, spontaneous S potentials (extracellularly recorded excitatory postsynaptic potentials) were preceded at a fixed interval by a small wave (the 'T' potential). In another 14 cells, a T potential, although not detected in single traces, was revealed by averaging 20-100 samples synchronized to the peak of the S potential. Provided the field response was not too large a T potential could also be detected in the response to a stimulus to the optic nerve. The T potential would appear to be the spike potential of the afferent optic axon which is excitatory to the geniculate cell because it precedes the S potential at a very exact interval and also follows the corresponding retinal ganglion cell spike at a very exact interval and because the interval between T potential and S potential is reversibly decreased by cooling with a temperature coefficient characteristic of synapses. T potentials ranged in amplitude from 8 to 134 microV and were all predominantly positive-going suggesting a failure of the nerve impulse to invade fully the terminals of the optic nerve. The time from the positive peak of the T potential to the start of the S potentials was taken as a good measure of the synaptic delay. The T-S interval averaged 0.29 ms (+/- 0.045 ms S.D.).
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0006-8993
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
23
|
pubmed:volume |
343
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
236-45
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2996696-Action Potentials,
pubmed-meshheading:2996696-Animals,
pubmed-meshheading:2996696-Cats,
pubmed-meshheading:2996696-Geniculate Bodies,
pubmed-meshheading:2996696-Neural Conduction,
pubmed-meshheading:2996696-Retinal Ganglion Cells,
pubmed-meshheading:2996696-Synapses,
pubmed-meshheading:2996696-Synaptic Transmission,
pubmed-meshheading:2996696-Visual Pathways
|
pubmed:year |
1985
|
pubmed:articleTitle |
Synaptic delay in the lateral geniculate nucleus of the cat.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|