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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1985-10-24
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pubmed:abstractText |
Two patients with insulinomas had unusual glucose and insulin-secretory dynamics in response to prolonged fasting. In patient 1, low insulin values persisted throughout three separate supervised fasts without a steady rise in the insulin-glucose ratio. In patient 2, a rising insulin-glucose ratio during a fast returned to normal after a documented catecholamine surge following a transient hypoglycemic episode. While patient 1 had clearly elevated proinsulin values of 52% to 57%, patient 2 had a near-normal value of 23%. The diagnosis of an insulinoma can usually be made by obtaining simultaneous glucose and insulin values during a prolonged supervised fast. Rarely, however, anomalous results may be obtained during supervised fasts of patients with insulinoma, and a broader range of diagnostic tests will be required to establish the correct diagnosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-9926
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1861-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:2994586-Adenoma, Islet Cell,
pubmed-meshheading:2994586-Aged,
pubmed-meshheading:2994586-Blood Glucose,
pubmed-meshheading:2994586-Catecholamines,
pubmed-meshheading:2994586-Fasting,
pubmed-meshheading:2994586-Female,
pubmed-meshheading:2994586-Humans,
pubmed-meshheading:2994586-Hypoglycemia,
pubmed-meshheading:2994586-Insulin,
pubmed-meshheading:2994586-Insulinoma,
pubmed-meshheading:2994586-Middle Aged,
pubmed-meshheading:2994586-Pancreatic Neoplasms
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pubmed:year |
1985
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pubmed:articleTitle |
Anomalous glucose and insulin responses in patients with insulinoma. Caveats for diagnosis.
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pubmed:publicationType |
Journal Article,
Case Reports
|