|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1985-9-27
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|
pubmed:abstractText |
The localization and mechanism of generation of active oxygen species in the enzymatic NADPH-dependent lipid peroxidation system in liver microsomes were studied. Using the spin-trapping method, the key role of active oxygen species in the initiation of NADPH-dependent enzymatic lipid peroxidation was confirmed. It was shown that active oxygen species are generated via consecutive one-electron reduction of the oxygen molecule by NADPH-cytochrome P-450 reductase.
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pubmed:language |
rus
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0320-9725
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
50
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
986-91
|
|
pubmed:dateRevised |
2007-7-23
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|
pubmed:meshHeading |
pubmed-meshheading:2992614-Animals,
pubmed-meshheading:2992614-Catalase,
pubmed-meshheading:2992614-Cytochrome Reductases,
pubmed-meshheading:2992614-Electron Spin Resonance Spectroscopy,
pubmed-meshheading:2992614-Electron Transport,
pubmed-meshheading:2992614-Endoplasmic Reticulum,
pubmed-meshheading:2992614-Free Radicals,
pubmed-meshheading:2992614-Intracellular Membranes,
pubmed-meshheading:2992614-Lipid Peroxides,
pubmed-meshheading:2992614-Microsomes, Liver,
pubmed-meshheading:2992614-NADH Dehydrogenase,
pubmed-meshheading:2992614-Rats,
pubmed-meshheading:2992614-Superoxide Dismutase
|
|
pubmed:year |
1985
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|
pubmed:articleTitle |
[Study of the mechanism of initiation of enzymatic NADPH-dependent lipid peroxidation in membranes of the endoplasmic reticulum].
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|
pubmed:publicationType |
Journal Article,
In Vitro,
English Abstract
|
