Linked Life Data

2990976

Source:http://linkedlifedata.com/resource/pubmed/id/2990976

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-9-19
pubmed:abstractText
Beta-sympathomimetic drugs are clinically widely used in the management of threatened premature labour. The existence of beta-adrenergic receptors has been demonstrated in the human placenta and, as the stimulation of beta-adrenoreceptors is known to be mediated by cAMP, the purpose of this study was to compare the effect of Ritodrinum on cAMP concentration in placentas of different gestational age. The in vitro treatment with Ritodrinum induced a five fold increase in cAMP concentration in 6-8 week old placenta, three fold increase in midgestation, but was without effect in term placenta. This result suggest that beta-mimetics in pharmacological concentrations could modulate trophoblast cell activity through the cAMP-dependent system during the first half of gestation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0232-7384
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
223-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
In vitro effect of ritodrinum on cAMP concentration in human placentas of different gestational age.
pubmed:publicationType
Journal Article, Comparative Study