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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1985-9-4
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pubmed:abstractText |
To investigate the actions of drugs and hormones which influence intraocular pressure (IOP), we have been measuring receptor binding characteristics and dose-response effects using individual target cells from the anterior segment. Similar methods have also permitted us to develop sensitive radio-receptor assays for glucocorticoids and beta adrenergic antagonists. These methods provide a means to obtain new and potentially useful information regarding the efficacy and specificity of ocular drug therapy.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0271-3683
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-79
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2990817-Animals,
pubmed-meshheading:2990817-Cattle,
pubmed-meshheading:2990817-Cell Line,
pubmed-meshheading:2990817-Cells, Cultured,
pubmed-meshheading:2990817-Ciliary Body,
pubmed-meshheading:2990817-Epithelial Cells,
pubmed-meshheading:2990817-Glaucoma,
pubmed-meshheading:2990817-Humans,
pubmed-meshheading:2990817-Muscles,
pubmed-meshheading:2990817-Parasympathomimetics,
pubmed-meshheading:2990817-Primates,
pubmed-meshheading:2990817-Radioligand Assay,
pubmed-meshheading:2990817-Receptors, Adrenergic,
pubmed-meshheading:2990817-Receptors, Cell Surface,
pubmed-meshheading:2990817-Receptors, Cholinergic,
pubmed-meshheading:2990817-Receptors, Glucocorticoid,
pubmed-meshheading:2990817-Sympathomimetics,
pubmed-meshheading:2990817-Trabecular Meshwork
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pubmed:year |
1985
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pubmed:articleTitle |
Isolation and evaluation of target cells in glaucoma research: hormone receptors and drug responses.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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