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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1985-8-5
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pubmed:abstractText |
Thirty penicillinase-producing Neisseria gonorrhoeae (PPNG) strains, 26 representing 9 serovars of the protein IB and 4 representing 2 serovars of the protein IA serogroup, had 10 different patterns when investigated by the restriction enzyme (RE) technique with Hind III enzyme. One RE pattern dominated, representing 11 strains with 6 different serovars of both the protein IA and IB serogroup. Identical serovars and RE patterns were found among 7 patients (3, 2 and 2, respectively) with positive epidemiology. The majority of the strains (24/30) were resistant to, or showed decreased sensitivity to, doxycycline with minimum inhibitory concentrations between 1 and 8 mg/l, consistent with the Far East origin. All the 30 PPNG strains showed by agarose gel electrophoresis to harbour a 2.8 Mdalton, a 4.4 Mdalton, as well as a 24.5 Mdalton plasmid, whereas the two non-PPNG strains had only the 2.8 Mdalton plasmid.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0108-0180
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
91-7
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pubmed:dateRevised |
2009-6-4
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pubmed:meshHeading |
pubmed-meshheading:2990157-DNA, Bacterial,
pubmed-meshheading:2990157-DNA Restriction Enzymes,
pubmed-meshheading:2990157-Doxycycline,
pubmed-meshheading:2990157-Drug Resistance, Microbial,
pubmed-meshheading:2990157-Gonorrhea,
pubmed-meshheading:2990157-Humans,
pubmed-meshheading:2990157-Neisseria gonorrhoeae,
pubmed-meshheading:2990157-Norway,
pubmed-meshheading:2990157-Penicillinase,
pubmed-meshheading:2990157-Plasmids,
pubmed-meshheading:2990157-Serotyping
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pubmed:year |
1985
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pubmed:articleTitle |
Phenotypic and genotypic characterization of penicillinase-producing strains of Neisseria gonorrhoeae.
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pubmed:publicationType |
Journal Article
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