Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1985-8-2
pubmed:databankReference
pubmed:abstractText
We have determined the nucleotide sequence of the yeast ILV2 gene which codes for the amino acid biosynthetic enzyme acetolactate synthase (ALS). ALS has recently been shown to be the target in bacteria, yeast and plants, of the potent new herbicide sulfometuron methyl. The coding sequence for the ILV2 polypeptide contains 2061 base pairs. Comparison of deduced amino acid sequences indicates considerable conservation between the yeast protein and the large subunits of the E. coli ALS II and ALS III isozymes. A major distinction between the three proteins is the presence of an additional 90 amino acids at the amino terminal of the yeast protein. The amino acid sequence in this region shows similarities to yeast mitochondrial transit sequences and may function as such, since yeast ALS is localized in the mitochondria. Consensus sequences for initiation and termination of transcription that are consistent with the ends of the ILV2 mRNA, as well as general amino acid control regulatory sequences have been identified.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-1195397, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-16663712, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-16663878, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-17793381, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-271968, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-3881312, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-4612003, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-4616942, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-5642457, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-5642458, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6090425, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6154938, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6268305, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6276387, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6280875, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6292893, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6294090, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6300123, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6308579, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6310345, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6329691, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6337724, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6343825, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6358221, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6360995, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6365533, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6378902, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6750137, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6791577, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-6805381, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-7015336, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-7037777, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-7039847, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989783-7049837
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0305-1048
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4011-27
pubmed:dateRevised
2010-9-9
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Nucleotide sequence of the yeast ILV2 gene which encodes acetolactate synthase.
pubmed:publicationType
Journal Article