Linked Life Data

2989740

Source:http://linkedlifedata.com/resource/pubmed/id/2989740

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-8-15
pubmed:abstractText
The light microscopic localization of gamma-aminobutyric acidB (GABAB) receptors in the rat brain has been accomplished using in vitro autoradiography with [3H]baclofen as a ligand. Initial biochemical studies indicated this compound specifically bound to slide-mounted tissue sections with high affinity in a saturable and readily reversible manner. Autoradiograms generated by labeled tissue sections demonstrated high grain densities over structures such as the interpeduncular nucleus, molecular layer of the cerebellum, superior colliculus, several thalamic nuclei and the superficial laminae of the cortex. The majority of the GABAB sites were found to exist in regions of the brain previously reported to have significant densities of GABA sites present. A few areas were noted, however, where the distribution of GABAA and GABAB sites did not overlap.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
183-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
gamma-Aminobutyric acidB receptors in the rat brain: quantitative autoradiographic localization using [3H](-)-baclofen.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.