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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-7-24
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pubmed:abstractText |
Immunologic and serologic studies were done in 120 homosexual men who reportedly had no symptoms related to the acquired immunodeficiency syndrome. Forty-nine men (41%) had antibody to the retrovirus human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV), and 37 (31%) had an abnormal T-cell subset ratio and other immunologic abnormalities. These abnormalities were almost exclusively confined to men seropositive for the retrovirus. Multivariate statistical analysis showed that exposure to HTLV-III/LAV was the single best predictor of T-cell (and other) immunologic abnormalities. Sexual practice, particularly receptive anal intercourse, predicted exposure to HTLV-III/LAV but was not independently related to T-cell abnormalities. The association of other microbial serologic findings with HTLV-III/LAV seropositivity or T-cell changes was a coincidental function of sexual activity. Immunologic abnormalities in asymptomatic homosexual men are mostly related to exposure to HTLV-III/LAV.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0003-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-42
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:2988389-Antibodies, Viral,
pubmed-meshheading:2988389-Antigen-Antibody Complex,
pubmed-meshheading:2988389-Deltaretrovirus,
pubmed-meshheading:2988389-Homosexuality,
pubmed-meshheading:2988389-Humans,
pubmed-meshheading:2988389-Immunoglobulins,
pubmed-meshheading:2988389-Leukocyte Count,
pubmed-meshheading:2988389-Lymphocyte Activation,
pubmed-meshheading:2988389-Male,
pubmed-meshheading:2988389-Mitogens,
pubmed-meshheading:2988389-Regression Analysis,
pubmed-meshheading:2988389-Retrospective Studies,
pubmed-meshheading:2988389-Sexual Behavior,
pubmed-meshheading:2988389-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:2988389-T-Lymphocytes, Regulatory
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pubmed:year |
1985
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pubmed:articleTitle |
Exposure to human T-lymphotropic virus type III/lymphadenopathy-associated virus and immunologic abnormalities in asymptomatic homosexual men.
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pubmed:publicationType |
Journal Article
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