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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1985-7-9
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pubmed:databankReference | |
pubmed:abstractText |
Several phosphoglycerate kinase genes were previously detected in the human genome by blot hybridization with a phosphoglycerate kinase cDNA probe. Using subcloned fragments of the cDNA we estimate the presence of four independent phosphoglycerate kinase genes. These genes have been mapped to both the human X chromosome (band q13) and chromosome 6 (p12-21.1) using a panel of human-rodent somatic cell hybrids and by chromosomal in situ hybridization. The genomic distribution of phosphoglycerate kinase sequences is conserved in man and mouse, not only for the X chromosome, but also for linkage to the respective major histocompatibility complexes. Molecular cloning of X-linked phosphoglycerate kinase sequences led to the identification of a novel intronless phosphoglycerate kinase pseudogene which is localized proximal to the active gene on the X chromosome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0021-9258
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
260
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6982-92
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2987238-Base Sequence,
pubmed-meshheading:2987238-Chromosome Banding,
pubmed-meshheading:2987238-Chromosome Mapping,
pubmed-meshheading:2987238-Chromosomes, Human, 6-12 and X,
pubmed-meshheading:2987238-DNA,
pubmed-meshheading:2987238-DNA Restriction Enzymes,
pubmed-meshheading:2987238-Female,
pubmed-meshheading:2987238-Genes,
pubmed-meshheading:2987238-HLA Antigens,
pubmed-meshheading:2987238-Humans,
pubmed-meshheading:2987238-Male,
pubmed-meshheading:2987238-Nucleic Acid Hybridization,
pubmed-meshheading:2987238-Phosphoglycerate Kinase,
pubmed-meshheading:2987238-X Chromosome
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pubmed:year |
1985
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pubmed:articleTitle |
The human phosphoglycerate kinase multigene family. HLA-associated sequences and an X-linked locus containing a processed pseudogene and its functional counterpart.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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