|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1985-7-3
|
|
pubmed:abstractText |
Phospholipase digestion of rat intestinal epithelial cell membranes was performed in order to study the influence of membrane phospholipids on the binding activity of VIP receptors. Phospholipases A2 and C strongly (ED50 congruent to 4 X 10(-2) and 4 X 10(-1) micrograms/ml, respectively) and rapidly reduced 125I-VIP binding to membranes whereas phospholipase D was ineffective. This suggests an important role of both hydrophobic and hydrophilic groups of phospholipids on VIP receptor binding activity.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0014-4754
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
41
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
631-3
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2987022-Animals,
pubmed-meshheading:2987022-Intestinal Mucosa,
pubmed-meshheading:2987022-Membrane Lipids,
pubmed-meshheading:2987022-Phospholipases,
pubmed-meshheading:2987022-Phospholipids,
pubmed-meshheading:2987022-Rats,
pubmed-meshheading:2987022-Receptors, Cell Surface,
pubmed-meshheading:2987022-Receptors, Vasoactive Intestinal Peptide,
pubmed-meshheading:2987022-Structure-Activity Relationship,
pubmed-meshheading:2987022-Vasoactive Intestinal Peptide
|
|
pubmed:year |
1985
|
|
pubmed:articleTitle |
Role of phospholipids in the binding activity of vasoactive intestinal peptide receptors.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
