rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
1985-4-15
|
pubmed:abstractText |
In a multi-centre double-blind (double-dummy) trial the effectiveness of low-dose antacid gel (6 X 12 ml/d; neutralisation capacity 120 mmol) was compared with that of a standard dose of cimetidine (1 g/d) in the curative treatment of gastric ulcer. Antacid gel was given to 65 patients, cimetidine to 60. Diagnosis was confirmed by endoscopic biopsy, which was also employed in a serial follow-up. After 4 weeks antacid gel and cimetidine produced cures in 43% and 52%, respectively; after 8 weeks 76% and 89%, respectively, the difference between the two methods not being statistically significant. There was also no statistically significant difference with regard to ulcer pain. In one case each in the antacid and cimetidine groups, the treatment had to be stopped because of side effects. Diarrhoea was more common on cimetidine than on antacid gel. It is concluded that both low-dose antacids gels and cimetidine are suitable in the treatment of gastric ulcers.
|
pubmed:language |
ger
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0012-0472
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
22
|
pubmed:volume |
110
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
283-7
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2982563-Adult,
pubmed-meshheading:2982563-Aged,
pubmed-meshheading:2982563-Aluminum Hydroxide,
pubmed-meshheading:2982563-Cimetidine,
pubmed-meshheading:2982563-Clinical Trials as Topic,
pubmed-meshheading:2982563-Double-Blind Method,
pubmed-meshheading:2982563-Drug Combinations,
pubmed-meshheading:2982563-Female,
pubmed-meshheading:2982563-Humans,
pubmed-meshheading:2982563-Magnesium,
pubmed-meshheading:2982563-Magnesium Hydroxide,
pubmed-meshheading:2982563-Male,
pubmed-meshheading:2982563-Middle Aged,
pubmed-meshheading:2982563-Placebos,
pubmed-meshheading:2982563-Silicic Acid,
pubmed-meshheading:2982563-Silicon Dioxide,
pubmed-meshheading:2982563-Smoking,
pubmed-meshheading:2982563-Stomach Ulcer
|
pubmed:year |
1985
|
pubmed:articleTitle |
[Therapy of stomach ulcer with low-dose antacid gel and cimetidine. A multicenter double-blind study].
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
|