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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1989-6-30
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pubmed:abstractText |
Apraclonidine (para-aminoclonidine) is an alpha agonist that was studied for its effect on the IOP rise following YPC. In a prospective multicentered double-masked study 63 eyes were pretreated with one drop of either 1% apraclonidine or placebo 1 hour prior to performing YAG and again after the laser treatment. The greatest IOP rise in the placebo-treated eyes occurred in the third hour after YPC when the mean IOP rose from a baseline pressure of 16.4 +/- 3.7 mm Hg to 20.8 +/- 6.8 mm Hg (P less than .01). In apraclonidine-treated eyes the IOP fell from a mean of 15.6 +/- 3.8 mm Hg to 12.8 +/- 6.0 mm Hg 3 hours postoperatively (P less than .001). There were five times as many eyes that had a pressure rise greater than 10 mm Hg in the placebo-treated group compared to those treated with apraclonidine. Apraclonidine proved to be highly effective in preventing the rise in IOP following YPC.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-2887153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3307716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3307717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3566598,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3785886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3839390,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3982799,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3985828,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3991123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-3991124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-4022582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-6486235,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-6497745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-6546789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-6547221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-6547424,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-6660258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-6672698,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2979050-7196390
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0065-9533
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
461-72
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2979050-Administration, Topical,
pubmed-meshheading:2979050-Aged,
pubmed-meshheading:2979050-Clonidine,
pubmed-meshheading:2979050-Female,
pubmed-meshheading:2979050-Glaucoma,
pubmed-meshheading:2979050-Humans,
pubmed-meshheading:2979050-Intraocular Pressure,
pubmed-meshheading:2979050-Laser Therapy,
pubmed-meshheading:2979050-Lens, Crystalline,
pubmed-meshheading:2979050-Lens Capsule, Crystalline,
pubmed-meshheading:2979050-Male,
pubmed-meshheading:2979050-Time Factors,
pubmed-meshheading:2979050-Tonometry, Ocular
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pubmed:year |
1988
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pubmed:articleTitle |
Effectiveness of apraclonidine in preventing the rise in intraocular pressure after neodymium:YAG posterior capsulotomy.
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pubmed:affiliation |
Wilmer Ophthalmology Institute, Department of Ophthalmology, Johns Hopkins University, Baltimore.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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