Linked Life Data

2964989

Source:http://linkedlifedata.com/resource/pubmed/id/2964989

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-5-5
pubmed:abstractText
Skin blood flow (SBF) in allergic and irritant reactions was determined by laser Doppler flowmetry (LDF) in an attempt to differentiate these reactions in an objective way. 12 subjects with known allergy to nickel were patch tested with nickel sulphate, nickel chloride, and with sodium lauryl sulphate (SLS) 1, 2, 5 and 10%. A positive correlation between the concentration of SLS and SBF was found. Compared with control sites, SBF in weak (+) and strong (++) positive allergic and irritant reactions was increased approximately 5-10 fold 1 and 2 days after application, and decreased towards normal 7 days after application. At day 7, the mean SBF was higher in allergic reactions than in irritant reactions. However, no consistent differences were found. It is concluded that although LDF can be used to quantify the strength of allergic and irritant skin reactions, this method cannot be used solely to separate these 2 types of reaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0105-1873
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Allergic and irritant skin reactions evaluated by laser Doppler flowmetry.
pubmed:affiliation
Department of Dermatology, Gentofte Hospital, Copenhagen, Denmark.
pubmed:publicationType
Journal Article