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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1988-3-29
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pubmed:abstractText |
It has been demonstrated that both elastin and tropoelastin preparations obtained from aortae of spontaneously hypertensive rats at the stage of established hypertension differ in their amino acid composition from age-matching controls. The differences refer to an increased proportion of polar amino acids, particularly aspartic and glutamic acid (about a two-fold increase compared to the controls) and arginine and tyrosine (1.5 times the control value). On the other hand, this increase is compensated for by a decrease in the valine concentration. Furthermore, direct estimation of the number of val-pro sequence in different elastin preparations indicated a drop from 49.3 to 29.2 per 1,000 residues in normotensive controls and preparations obtained from spontaneously hypertensive rats respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0369-9463
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
481-5
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2964043-Amino Acids,
pubmed-meshheading:2964043-Animals,
pubmed-meshheading:2964043-Aorta,
pubmed-meshheading:2964043-Elastin,
pubmed-meshheading:2964043-Hypertension,
pubmed-meshheading:2964043-Rats,
pubmed-meshheading:2964043-Rats, Inbred SHR,
pubmed-meshheading:2964043-Tropoelastin
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pubmed:year |
1987
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pubmed:articleTitle |
Changes in the blood vessel wall elastin of spontaneously hypertensive (SHR) rats.
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pubmed:affiliation |
Department of Biomechanics, Bulgarian Academy of Sciences, Sofia.
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pubmed:publicationType |
Journal Article
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