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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1988-4-1
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pubmed:abstractText |
beta-hydroxybutyrate dehydrogenase (BDH), a major protein located in the inner mitochondrial membrane is encoded, as most of mitochondrial proteins, in the nuclear genome. It is synthetized on the free polysomes and post-translationally imported into the mitochondria. The neosynthesized protein is a higher molecular weight precursor. The presequence is cleaved by the matrix protease to give the mature protein. The translocation across the mitochondrial membranes needs energy. The results also indicate that cytosolic factors with low molecular weight are essential in the recognition of precursor by mitochondria and to sort out newly synthetized nuclear encoded mitochondrial proteins from others nuclear encoded proteins.
|
pubmed:language |
fre
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0037-9026
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
181
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
389-94
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2963676-Animals,
pubmed-meshheading:2963676-Gene Expression Regulation,
pubmed-meshheading:2963676-Hydroxybutyrate Dehydrogenase,
pubmed-meshheading:2963676-Mitochondria,
pubmed-meshheading:2963676-Polyribosomes,
pubmed-meshheading:2963676-Protein Biosynthesis,
pubmed-meshheading:2963676-Rats
|
pubmed:year |
1987
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pubmed:articleTitle |
[Gene expression of D-beta-hydroxybutyrate dehydrogenase. II. Incorporation of pre-BDH into mitochondria].
|
pubmed:affiliation |
Laboratoire de Biochimie UA CNRS 531, Université de Franche-Comté, Besançon, France.
|
pubmed:publicationType |
Journal Article,
In Vitro,
English Abstract,
Research Support, Non-U.S. Gov't
|