Linked Life Data

2963521

Source:http://linkedlifedata.com/resource/pubmed/id/2963521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-3-2
pubmed:abstractText
Aortic regurgitation (AR) may result in overestimation of the aortic pressure gradient by continuous wave Doppler in patients with mixed aortic valve disease. However, few data are available regarding the effect of AR on noninvasive estimates of aortic valve area by the continuity equation. Therefore, 25 patients with angiographically documented severe AR and peak systolic aortic velocities of greater than 2.5 m/s were studied by continuous wave Doppler to determine the accuracy of pressure gradient and aortic valve area calculations in assessing the severity of aortic stenosis (AS) in this patient population. Peak instantaneous pressure gradient showed a general correlation to but was overestimated by Doppler (r = 0.78, Doppler = 0.70 catheter + 19.9) and did not predict aortic valve area. Mean pressure gradient by Doppler correlated more closely with catheter mean gradient (r = 0.86, Doppler = 0.79 catheter + 6.1) but was a poor predictor of the severity of AS. In contrast, the continuity equation accurately predicted the aortic valve area by catheterization (r = 0.92, Doppler = 0.89 catheter -0.08). Thus, the continuity equation provides a reliable estimate of aortic valve area in patients with severe AR and should be used to evaluate the extent of AS in such patients when high systolic aortic velocities are present.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
376-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Pivotal role of aortic valve area calculation by the continuity equation for Doppler assessment of aortic stenosis in patients with combined aortic stenosis and regurgitation.
pubmed:affiliation
Division of Cardiovascular Medicine, University of Kentucky, Lexington.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't