Linked Life Data

2960786

Source:http://linkedlifedata.com/resource/pubmed/id/2960786

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1987-12-22
pubmed:abstractText
Fifty-one families of patients affected with Huntington's chorea were interviewed with respect to age at onset, symptoms at onset and course of the disease. The interview further comprised questions pertinent to line of transmission, socio-economic status, housing, previous illnesses and pregnancy and stillbirth. Since the study was set up as a fishing expedition detailed quantitative information was gathered on many life-style factors including eating, drinking and smoking habits. In adult age onset cases earlier age at onset correlated with lower rate of progression. Line of transmission was of no influence on age at onset in cases with onset above 20 years. No statistically significant relationship was found between any factor studied and age at onset, except for the intake of milk. Higher previous milk intake was associated with earlier ages at onset. This finding is critically discussed. No difference was found between the respective ages at onset of conduct disorders and affective disorders. This suggests that they are both associated with the Huntington gene.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-510X
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
299-306
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Which factors influence age at onset and rate of progression in Huntington's disease?
pubmed:affiliation
Department of Neurology, Academic Hospital Leiden, The Netherlands.
pubmed:publicationType
Journal Article