pubmed-article:2959284 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2959284 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:2959284 | lifeskim:mentions | umls-concept:C0123711 | lld:lifeskim |
pubmed-article:2959284 | lifeskim:mentions | umls-concept:C0037791 | lld:lifeskim |
pubmed-article:2959284 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:2959284 | pubmed:dateCreated | 1987-11-12 | lld:pubmed |
pubmed-article:2959284 | pubmed:abstractText | The specificity of the type 2 insulinlike growth factor (IGF) receptor is evaluated in human placenta membranes and the human cell line K562. K562 cells have type 2 but not type 1 IGF receptors. Native IGF-2 isolated from human plasma and synthetic IGF-2 were equipotent in competing with labeled IGF-2 in both systems. Pure IGF-1 isolated from plasma, synthetic IGF-1 and recombinant IGF-1 could not crossreact with the type 2 IGF receptor in concentrations up to 1 microgram/ml in both systems. Studies on placenta membrane were done in the presence of 300 ug/ml insulin to block the type 1 IGF receptors. It is concluded that IGF-1, as well as insulin, cannot crossreact with the human type 2 IGF receptor. | lld:pubmed |
pubmed-article:2959284 | pubmed:language | eng | lld:pubmed |
pubmed-article:2959284 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2959284 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2959284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2959284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2959284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2959284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2959284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2959284 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2959284 | pubmed:month | Sep | lld:pubmed |
pubmed-article:2959284 | pubmed:issn | 0006-291X | lld:pubmed |
pubmed-article:2959284 | pubmed:author | pubmed-author:LiC HCH | lld:pubmed |
pubmed-article:2959284 | pubmed:author | pubmed-author:HallKK | lld:pubmed |
pubmed-article:2959284 | pubmed:author | pubmed-author:EnbergGG | lld:pubmed |
pubmed-article:2959284 | pubmed:author | pubmed-author:TallyMM | lld:pubmed |
pubmed-article:2959284 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2959284 | pubmed:day | 30 | lld:pubmed |
pubmed-article:2959284 | pubmed:volume | 147 | lld:pubmed |
pubmed-article:2959284 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2959284 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2959284 | pubmed:pagination | 1206-12 | lld:pubmed |
pubmed-article:2959284 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
pubmed-article:2959284 | pubmed:meshHeading | pubmed-meshheading:2959284-... | lld:pubmed |
pubmed-article:2959284 | pubmed:meshHeading | pubmed-meshheading:2959284-... | lld:pubmed |
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pubmed-article:2959284 | pubmed:meshHeading | pubmed-meshheading:2959284-... | lld:pubmed |
pubmed-article:2959284 | pubmed:meshHeading | pubmed-meshheading:2959284-... | lld:pubmed |
pubmed-article:2959284 | pubmed:meshHeading | pubmed-meshheading:2959284-... | lld:pubmed |
pubmed-article:2959284 | pubmed:meshHeading | pubmed-meshheading:2959284-... | lld:pubmed |
pubmed-article:2959284 | pubmed:year | 1987 | lld:pubmed |
pubmed-article:2959284 | pubmed:articleTitle | The specificity of the human IGF-2 receptor. | lld:pubmed |
pubmed-article:2959284 | pubmed:affiliation | Department of Endocrinology, Karolinska Institutet, Stockholm, Sweden. | lld:pubmed |
pubmed-article:2959284 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2959284 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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