rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1987-10-13
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pubmed:databankReference |
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pubmed:abstractText |
A cDNA clone encoding the mouse Ly-17+ Fc receptor for IgG, isolated from a myelomonocytic cell line, was sequenced and expression of mRNA and the functional Fc gamma R investigated. The receptor is a 301 amino acid transmembrane glycoprotein with two homologous extracellular domains that are also homologous to members of the Ig superfamily. The receptor has four sites of N-linked glycosylation and a long 94 amino acid cytoplasmic tail. Northern analysis, immune complex binding, and serological studies demonstrate that the receptor encoded by the cDNA clone binds mouse IgG gamma 1/2b and rabbit IgG complexes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Ly,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/Oligodeoxyribonucleotides,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fc,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, IgG
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pubmed:status |
MEDLINE
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pubmed:issn |
0093-7711
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2957319-Amino Acid Sequence,
pubmed-meshheading:2957319-Animals,
pubmed-meshheading:2957319-Antibodies, Monoclonal,
pubmed-meshheading:2957319-Antigens, Ly,
pubmed-meshheading:2957319-Base Sequence,
pubmed-meshheading:2957319-Cell Line,
pubmed-meshheading:2957319-Cloning, Molecular,
pubmed-meshheading:2957319-DNA,
pubmed-meshheading:2957319-Gene Expression Regulation,
pubmed-meshheading:2957319-Genes,
pubmed-meshheading:2957319-Mice,
pubmed-meshheading:2957319-Oligodeoxyribonucleotides,
pubmed-meshheading:2957319-RNA, Messenger,
pubmed-meshheading:2957319-Receptors, Fc,
pubmed-meshheading:2957319-Receptors, IgG,
pubmed-meshheading:2957319-Sequence Homology, Nucleic Acid
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pubmed:year |
1987
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pubmed:articleTitle |
The mouse Fc receptor for IgG (Ly-17): molecular cloning and specificity.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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