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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1987-8-28
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pubmed:abstractText |
Specific granules in porcine hearts were observed in atrial cardiocytes, Purkinje fibers, and transitional cells of the ventricle. These granule-containing cells were immunohistochemically stained by applying the avidin-biotin-peroxidase complex method using an antiserum against alpha-human atrial natriuretic polypeptide (ANP). Immunoelectron microscopy of sections stained using the immunogold method indicated that these specific granules are storage sites of ANP. Furthermore, an impulse-conducting system consisting of immunoreactive cells was clearly distinguishable from nonimmunoreactive ventricular cardiocytes. We conclude that specific-granule-containing cells, i.e., ANP-producing cells, are located in both the atrial walls and the ventricular impulse-conducting system. The presence of ANP may be correlated with impulse conduction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0301-5564
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
595-601
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2956221-Animals,
pubmed-meshheading:2956221-Atrial Natriuretic Factor,
pubmed-meshheading:2956221-Cytoplasmic Granules,
pubmed-meshheading:2956221-Histocytochemistry,
pubmed-meshheading:2956221-Immunochemistry,
pubmed-meshheading:2956221-Microscopy, Electron,
pubmed-meshheading:2956221-Myocardium,
pubmed-meshheading:2956221-Purkinje Fibers,
pubmed-meshheading:2956221-Swine
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pubmed:year |
1987
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pubmed:articleTitle |
Immunohistochemistry and immunocytochemistry of atrial natriuretic polypeptide in porcine heart.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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