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pubmed-article:2953126pubmed:abstractTextEndogenous factors preferentially inhibiting T-lymphocyte proliferation were prepared from the acetone precipitate of a 60% ethanol extract from calf thymus and their biochemical properties examined. By ultrafiltration the strongest lymphocyte-selective inhibition was found in the molecular mass range between 1 and 5 kDa. Fast protein liquid chromatography (FPLC) of this fraction on an anion exchange column eluted the lymphocyte inhibitors at 205-265 mM ammonium acetate. Staining procedures following IEF and TLC suggested, that the inhibitors may not be glycoconjugates or amines but small weakly acidic peptides (less than 3 kDa).lld:pubmed
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pubmed-article:2953126pubmed:authorpubmed-author:MaurerH RHRlld:pubmed
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pubmed-article:2953126pubmed:articleTitleLow molecular mass inhibitors from calf thymus selective for T-lymphocyte proliferation.lld:pubmed
pubmed-article:2953126pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2953126pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed