Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11-12
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pubmed:dateCreated |
1987-5-22
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pubmed:abstractText |
Endogenous factors preferentially inhibiting T-lymphocyte proliferation were prepared from the acetone precipitate of a 60% ethanol extract from calf thymus and their biochemical properties examined. By ultrafiltration the strongest lymphocyte-selective inhibition was found in the molecular mass range between 1 and 5 kDa. Fast protein liquid chromatography (FPLC) of this fraction on an anion exchange column eluted the lymphocyte inhibitors at 205-265 mM ammonium acetate. Staining procedures following IEF and TLC suggested, that the inhibitors may not be glycoconjugates or amines but small weakly acidic peptides (less than 3 kDa).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0939-5075
|
pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1131-6
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pubmed:dateRevised |
2009-11-4
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pubmed:meshHeading |
pubmed-meshheading:2953126-Animals,
pubmed-meshheading:2953126-Cattle,
pubmed-meshheading:2953126-Concanavalin A,
pubmed-meshheading:2953126-DNA Replication,
pubmed-meshheading:2953126-Lymphocyte Activation,
pubmed-meshheading:2953126-Mice,
pubmed-meshheading:2953126-Peptides,
pubmed-meshheading:2953126-T-Lymphocytes,
pubmed-meshheading:2953126-Thymus Gland
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pubmed:articleTitle |
Low molecular mass inhibitors from calf thymus selective for T-lymphocyte proliferation.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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