| pubmed-article:2952812 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2952812 | lifeskim:mentions | umls-concept:C0019169 | lld:lifeskim |
| pubmed-article:2952812 | lifeskim:mentions | umls-concept:C0062527 | lld:lifeskim |
| pubmed-article:2952812 | lifeskim:mentions | umls-concept:C0178795 | lld:lifeskim |
| pubmed-article:2952812 | lifeskim:mentions | umls-concept:C0062525 | lld:lifeskim |
| pubmed-article:2952812 | lifeskim:mentions | umls-concept:C1521797 | lld:lifeskim |
| pubmed-article:2952812 | lifeskim:mentions | umls-concept:C1708528 | lld:lifeskim |
| pubmed-article:2952812 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:2952812 | pubmed:dateCreated | 1987-5-29 | lld:pubmed |
| pubmed-article:2952812 | pubmed:abstractText | A yeast-recombinant hepatitis B vaccine was licensed recently by the Food and Drug Administration and is now available. To assess the efficacy of the yeast-recombinant vaccine, we administered the vaccine in combination with hepatitis B immune globulin to high-risk newborns. If infants whose mothers were positive for both hepatitis B surface antigen and the e antigen receive no immunoprophylaxis, 70% to 90% become infected with the virus, and almost all become chronic carriers. Among infants in this study who received hepatitis B immune globulin at birth and three 5-micrograms doses of yeast-recombinant hepatitis B vaccine, only 4.8% became chronic carriers, a better than 90% level of protection and a rate that is comparable with that seen with immune globulin and plasma-derived hepatitis B vaccine. These data suggest that, in this high-risk setting, the yeast-recombinant vaccine is as effective as the plasma-derived vaccine in preventing hepatitis B virus infection and the chronic carrier state. | lld:pubmed |
| pubmed-article:2952812 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2952812 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2952812 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2952812 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2952812 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2952812 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2952812 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2952812 | pubmed:month | May | lld:pubmed |
| pubmed-article:2952812 | pubmed:issn | 0098-7484 | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:KrugmanSS | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:TongM JMJ | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:VyasG NGN | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:StevensC ECE | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:ToyP TPT | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:TaylorP EPE | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:NairP VPV | lld:pubmed |
| pubmed-article:2952812 | pubmed:author | pubmed-author:WeissmanJ YJY | lld:pubmed |
| pubmed-article:2952812 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2952812 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:2952812 | pubmed:volume | 257 | lld:pubmed |
| pubmed-article:2952812 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2952812 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2952812 | pubmed:pagination | 2612-6 | lld:pubmed |
| pubmed-article:2952812 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:2952812 | pubmed:meshHeading | pubmed-meshheading:2952812-... | lld:pubmed |
| pubmed-article:2952812 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2952812 | pubmed:articleTitle | Yeast-recombinant hepatitis B vaccine. Efficacy with hepatitis B immune globulin in prevention of perinatal hepatitis B virus transmission. | lld:pubmed |
| pubmed-article:2952812 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2952812 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2952812 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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