Linked Life Data

2948365

Source:http://linkedlifedata.com/resource/pubmed/id/2948365

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-2-11
pubmed:abstractText
Atria of several mammalian species contain atrial natriuretic polypeptides (ANP) with natriuretic, diuretic, and vasodilating activity. In the present studies ANP were localized and quantitated in different parts of the heart by immunocytochemical and radioimmunological methods. The concentration of immunoreactive ANP as determined by quantitative radioimmunoassay in rat heart atria was a follows (ng/mg, mean +/- SD, n = 5): right auricle (688 +/- 156), left auricle (556 +/- 156), right atrium (334 +/- 60), and left atrium (93 +/- 36). The staining intensities in immunohistochemical localizations were consistent with the quantitative data. The location of the peptides was sarcoplasmic and granular. The highest concentration of ANP was found in the perinuclear area of the atrial myocyte sarcoplasm, but some staining was also seen in the periphery of the cells. The indirect immunoelectron microscopical gold method showed that ANP are located in the specific atrial granules supporting previous findings.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-1281
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-28
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Atrial natriuretic polypeptides in the specific atrial granules of the rat heart: immunohistochemical and immunoelectron microscopical localization and radioimmunological quantification.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't