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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1987-1-21
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pubmed:abstractText |
T-lymphocyte subpopulations were measured in the two major types of adult malnutrition, adult marasmus and kwashiorkor-like hypoalbuminemic malnutrition. The population of T-cells (T3) and the percentage of both helper (T4) and suppressor (T8) T-cells were significantly (P less than .05) decreased in patients with kwashiorkor-like hypoalbuminemic malnutrition, but did not differ from control values in patients with adult marasmus. The ratio of helper T-cell (T4), to suppressor T-cells (T8) (range 1.2-1.6) did not vary from control values in either type of malnutrition. One week of nutritional support was not associated with a significant increase in any of the T lymphocyte subpopulations in either type of malnutrition. These T-cell subpopulation changes are consistent with the greater depression of cellular immune function seen in patients with metabolic stresses associated with kwashiorkor-like hypoalbuminemic malnutrition. With the increasing frequency in which abnormalities of T-cell subpopulations are being reported in various diseases, the coexistence of kwashiorkor-like hypoalbuminemic malnutrition should be noted for its potentially confounding effect.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0731-5724
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
577-84
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pubmed:dateRevised |
2008-6-23
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pubmed:meshHeading |
pubmed-meshheading:2946750-Adult,
pubmed-meshheading:2946750-Female,
pubmed-meshheading:2946750-Humans,
pubmed-meshheading:2946750-Kwashiorkor,
pubmed-meshheading:2946750-Leukocyte Count,
pubmed-meshheading:2946750-Male,
pubmed-meshheading:2946750-Middle Aged,
pubmed-meshheading:2946750-Protein-Energy Malnutrition,
pubmed-meshheading:2946750-T-Lymphocytes,
pubmed-meshheading:2946750-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:2946750-T-Lymphocytes, Regulatory
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pubmed:year |
1986
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pubmed:articleTitle |
The effect of nutritional support on T-lymphocyte subpopulations in protein calorie malnutrition.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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