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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1986-12-18
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pubmed:abstractText |
The phototoxicity of hematoporphyrin derivative (Hpd) to murine bladder tumor (MBT-2) cells was studied in vitro. It was observed that selenium in the form of sodium selenite enhanced Hpd-sensitized photodamage in MBT-2 cells under conditions where selenite alone was non-toxic. Sodium selenite enhanced the fluorescence emission of Hpd and augmented the Hpd-sensitized photooxidation of tryptophan. The data suggest that sodium selenite is able to disaggregate Hpd, thereby enhancing Hpd-sensitized phototoxicity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1086-92
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2946295-Animals,
pubmed-meshheading:2946295-Cell Line,
pubmed-meshheading:2946295-Cell Survival,
pubmed-meshheading:2946295-Drug Interactions,
pubmed-meshheading:2946295-Hematoporphyrin Derivative,
pubmed-meshheading:2946295-Hematoporphyrins,
pubmed-meshheading:2946295-Light,
pubmed-meshheading:2946295-Mice,
pubmed-meshheading:2946295-Photochemistry,
pubmed-meshheading:2946295-Selenious Acid,
pubmed-meshheading:2946295-Selenium,
pubmed-meshheading:2946295-Spectrometry, Fluorescence,
pubmed-meshheading:2946295-Tryptophan,
pubmed-meshheading:2946295-Urinary Bladder Neoplasms
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pubmed:year |
1986
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pubmed:articleTitle |
Selenium-induced enhancement of hematoporphyrin derivative phototoxicity in murine bladder tumor cells.
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pubmed:publicationType |
Journal Article
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