Linked Life Data

294149

Source:http://linkedlifedata.com/resource/pubmed/id/294149

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1980-3-27
pubmed:abstractText
The effects of different prostaglandins were determined on (a) the hyperalgesia produced by subplantar injections of yeast given into the hind paws of weanling rats, and (b) the reflex vasopressor responses to bradykinin (BK) injected dose-arterially into the spleen of anaesthetised cats and dogs. In the rat prostaglandins (E1 greater than E2 greater than F2 alpha = F2 beta=A2=D2=I2O) injected into the same paw either with the yeast or 25 min later reduced the latency to the onset of hyperalgesia. In the cat and dog prostaglandins (E1 greater than E2 greater than F2 alpha greater than or equal to F2 beta greater than A1=A2=O) potentiated vasopressor responses to BK and reversed the inhibition of BK responses by indomethacin. It is likely that prostaglandins sensitize peripheral nociceptors through a specific prostaglandin receptor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0379-0363
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-78
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Effects of prostaglandins on peripheral nociceptors in acute inflammation.
pubmed:publicationType
Journal Article