Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1986-2-19
|
pubmed:abstractText |
beta-Endorphin (beta-EP) levels were measured in 13 post-menopausal women (7 surgical, 6 physiological) using a new highly specific and accurate radioimmunoassay, and were found to be significantly lower than among 10 normally menstruating controls (48.6 +/- 13.8 pg/ml vs. 70.0 +/- 18 pg/ml, P less than 0.005). beta-EP levels were measured prior to and 5 days after surgery in 3 of the oophorectomized women, and were found to have decreased by an average of 41%. beta-EP levels were measured immediately after hot flashes experienced by 4 of the post-menopausal women during regular clinic visits, and were found to be significantly elevated above baseline levels (P less than 0.02). Our data confirmed the findings of Genazzani et al. [10], a significant lowering of beta-EP at menopause. Also, the data from the small number of beta-EP plasma levels we studied during hot flashes, suggests a possible role of beta-EP either directly or indirectly on the genesis of hot flashes.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0378-5122
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
329-34
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2934609-Adult,
pubmed-meshheading:2934609-Climacteric,
pubmed-meshheading:2934609-Endorphins,
pubmed-meshheading:2934609-Female,
pubmed-meshheading:2934609-Humans,
pubmed-meshheading:2934609-Menopause,
pubmed-meshheading:2934609-Middle Aged,
pubmed-meshheading:2934609-Ovariectomy,
pubmed-meshheading:2934609-Radioimmunoassay,
pubmed-meshheading:2934609-Syndrome,
pubmed-meshheading:2934609-beta-Endorphin
|
pubmed:year |
1985
|
pubmed:articleTitle |
Menopausal syndrome: plasma levels of beta-endorphin in post-menopausal women measured by a specific radioimmunoassay.
|
pubmed:publicationType |
Journal Article
|