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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1985-12-13
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pubmed:abstractText |
Alterations in the autologous mixed lymphocyte reaction (autologous MLR) have been reported in many autoimmune diseases and in diseases with a derangement of T regulatory function. We have studied autologous MLR in 10 patients with idiopathic autoimmune hemolytic anemia (IAHA). All patients had decreased autologous MLR which averaged 4,106 +/- 1,332 cpm (SEM) compared to 12,153 +/- 4,166 cpm for simultaneously studied controls. A marked decrease in phytohemagglutinin response and an imbalance of T-cell subsets were also observed. These findings suggest a possible abnormality of T immunoregulatory function in IAHA patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0042-9007
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
285-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2932854-Adult,
pubmed-meshheading:2932854-Aged,
pubmed-meshheading:2932854-Anemia, Hemolytic, Autoimmune,
pubmed-meshheading:2932854-Autoantigens,
pubmed-meshheading:2932854-Female,
pubmed-meshheading:2932854-Humans,
pubmed-meshheading:2932854-Isoantigens,
pubmed-meshheading:2932854-Lymphocyte Activation,
pubmed-meshheading:2932854-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:2932854-Male,
pubmed-meshheading:2932854-Middle Aged,
pubmed-meshheading:2932854-Phytohemagglutinins,
pubmed-meshheading:2932854-T-Lymphocytes
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pubmed:year |
1985
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pubmed:articleTitle |
Deficiency of autologous mixed lymphocyte reaction in patients with idiopathic autoimmune hemolytic anemia.
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pubmed:publicationType |
Journal Article
|