Linked Life Data

2931556

Source:http://linkedlifedata.com/resource/pubmed/id/2931556

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-11-12
pubmed:abstractText
The distribution of specific mineralocorticoid receptors in rat kidney cells was found to depend on aldosterone concentration. With increasing aldosterone concentrations the number of specific receptors for aldosterone in the cytoplasm decreased and their quantity in the nuclei increased. This was evidently due to their enhanced transport from the cytoplasm to the nuclei. It was found that aldosterone (its complex with the receptor) attached to non-histone proteins of chromatin and that the structural integrity of DNA is needed to provide the binding of this complex to the cell nuclei. The quantity of aldosterone acceptor sites in the kidney cell nuclei remained constant when aldosterone concentrations in the organism changed, and, hence, the functional states of the target organ changed too.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-4731
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
333-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
A study of [3H]aldosterone binding by nuclear and cytoplasmic receptors of the rat kidney with different content of aldosterone in the organism.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro