Linked Life Data

2928647

Source:http://linkedlifedata.com/resource/pubmed/id/2928647

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-4-27
pubmed:abstractText
The binding of toxic shock syndrome toxin 1 (TSST-1) to the endothelium of human umbilical cord veins and arteries was studied. Radiolabeled TSST-1, perfused through a segment of human umbilical cord vein, bound to the vessel at 4 degrees C, with a dissociation constant (Kd) of 6.5 X 10(-10) M. A pre-embedding electron-microscopic immunogold technique revealed that TSST-1 was located in the veins and arteries on the surface of endothelial cells and in the area of cell contacts. Umbilical cord vein segments filled with TSST-1 were incubated for 30 minutes at 37 degrees C, fixed by perfusion and embedded in hydrophilic resin (Lowicryl K4M). Postembedding immunogold staining of ultrathin sections showed TSST-1 in the vesicles crossing the cytoplasm of the veins' endothelial cells and entering underlying elastic and collagen layers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0162-0886
pubmed:author
pubmed:issnType
Print
pubmed:volume
11 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S282-7; discussion S287-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Reaction of toxic shock syndrome toxin 1 with endothelium of human umbilical cord vein.
pubmed:affiliation
Department of Microbiology, Medical College of Wisconsin, Milwaukee 53226.
pubmed:publicationType
Journal Article