Linked Life Data

2924163

Source:http://linkedlifedata.com/resource/pubmed/id/2924163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-4-28
pubmed:abstractText
Microdialysis probes inserted into chronically implanted guide shafts allowed the collection of serotonin and 5-hydroxyindoleacetic acid (5-HIAA) from the lateral hypothalamus of rats during feeding behavior. After the collection of baseline samples, animals were offered a palatable diet that they could only see and smell for 60 min, then they were allowed access to the food for an hour. An additional three samples were collected after food was removed. Extracellular serotonin increased during the first half hour of access when the animals actually ate the food, and then returned to baseline level throughout the remainder of the test. 5-HIAA decreased gradually with no increase during feeding. These data suggest that eating a meal of palatable food causes a short-term increase in extracellular serotonin in the lateral hypothalamus. This increased serotonin may play a role in the control of lateral hypothalamic feeding and reward.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
479
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
349-54
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Feeding increases extracellular serotonin in the lateral hypothalamus of the rat as measured by microdialysis.
pubmed:affiliation
Department of Psychology, Princeton University, NJ 08544.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't