Linked Life Data

2919136

Source:http://linkedlifedata.com/resource/pubmed/id/2919136

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-4-6
pubmed:abstractText
The mean number of cells per cartilage column and the proportion of hypertrophic and proliferative chondrocytes per column were determined in the costochondral junction in a population of normal subjects including 10 fetal-newborns and 15 subjects aged 0.3-16 y of age. Both the mean number of cells per column and the proportion of proliferative cells per column were significantly greater in the fetal-newborn population compared to the pediatric population (12.6 +/- 1.0 versus 8.4 +/- 0.4, p less than 0.001 and 39.6 +/- 6.9 versus 24.4 +/- 2.5, p = 0.025, respectively) (mean +/- sem [n]). The number of cells per column bore a significant negative relationship to subject age (r = -0.52, p = 0.007). Significant positive correlations were found between the mean number of cells per column and age-specific growth velocity both in males (length-height velocity = [(6.3) (mean number of cells) - 44.1], r = 0.72, p = 0.02) and in females (length-height velocity = [(3.4 (mean number of cells) - 14.4], r = 0.77, p = 0.006). These data will provide normative values against which abnormalities characteristic of the skeletal dysplasias can be compared.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0031-3998
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
202-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Quantitative histology of cartilage cell columns in the human costochondral junction: findings in newborn and pediatric subjects.
pubmed:affiliation
Medical Genetics-Birth Defects Center, Cedars-Sinai Medical Center, Los Angeles, California 90048.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.